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publications

Association between ambient temperature and mortality risk and burden: time series study in 272 main Chinese cities

Objectives To examine the association between temperature and cause specific mortality, and to quantify the corresponding disease burden attributable to non-optimum ambient temperatures. Introduction In the context of global climate change, accumulating epidemiological evidence indicates that abnormal ambient temperatures could […]
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Mirtazapine added to SSRIs or SNRIs for treatment resistant depression in primary care: phase III randomised placebo controlled trial (MIR)

Objective To investigate the effectiveness of combining mirtazapine with serotonin-noradrenaline reuptake inhibitor (SNRI) or selective serotonin reuptake inhibitor (SSRI) antidepressants for treatment resistant depression in primary care. Introduction Depression is among the top five contributors to the global burden of […]
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Evaluation of the diet wide contribution to serum urate levels: meta-analysis of population based cohorts

Objective To systematically test dietary components for association with serum urate levels and to evaluate the relative contributions of estimates of diet pattern and inherited genetic variants to population variance in serum urate levels. Read more
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Effectiveness of the Stand More AT (SMArT) Work intervention: cluster randomised controlled trial

Objectives To evaluate the impact of a multicomponent intervention (Stand More AT (SMArT) Work) designed to reduce sitting time on short (three months), medium (six months), and longer term (12 months) changes in occupational, daily, and prolonged sitting, standing, and […]
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